Benjamin A Nanes, MD, PhD
Instructor
Department of Dermatology
Danuser Lab, Lyda Hill Department of Bioinformatics
UT Southwestern Medical Center

A Molecular Basis for Dynamic Tissue Architecture

How does the epidermis balance strength and plasticity?

As the barrier between the organism and the outside world, the epidermis routinely encounters, and must resist, mechanical stress. Yet the epidermis also regularly undergoes remodeling to repair even minor wounds. This represents the fundamental architectural challenge of the epidermis—balancing strength and plasticity.

My research focuses on the molecular basis for this balance. Protein complexes called cytoskeletons establish cell shape, generate force, and ultimately determine tissue architecture. Using tissue engineering, advanced imaging, and computer vision pipelines to measure cytoskeleton networks and their interactions, I study how the cellular machinery drives epidermal remodeling during wound healing.

Advisor: Gaudenz Danuser, PhD (lab website)

Support:
UT Southwestern Physician Scientist Training Program
Dermatology Foundation
NIH T32 AR065969

PubMed search

How to Create Publication-Quality Figures

Software

Training

Residency

Department of Dermatology
UT Southwestern Medical Center

Internship

Department of Internal Medicine
UT Southwestern Medical Center

MD

Emory University School of Medicine

PhD — Dynamic regulation of endothelial cell adhesion

Emory University School of Medicine
Biochemistry, Cell, and Developmental Biology
Advisor: Andrew Kowalczyk, PhD (lab website)

Profiles

NCBI My Bibliography
ORCID iD iconORCID
Github
@BenjaminNanes